This guide contains information about places where you can stop for the night when driving from Daytona Beach, Florida to Myrtle Beach, South Carolina. Total distance for the trip is around 447 miles with a driving time of approximately 6 hours 44 mins. Cities and towns with hotels that are on the fastest route between Daytona Beach and Myrtle Beach are listed below. (Driving times are approximate and will vary with traffic and weather conditions.)

89.1 miles from Daytona Beach (1 hour 26 mins)
358 miles from Myrtle Beach (5 hours 20 mins)
159 miles from Daytona Beach (2 hours 26 mins)
297 miles from Myrtle Beach (4 hours 33 mins)
228 miles from Daytona Beach (3 hours 22 mins)
226 miles from Myrtle Beach (3 hours 36 mins)
328 miles from Daytona Beach (4 hours 59 mins)
95.6 miles from Myrtle Beach (1 hour 57 mins)

Popular Hotels In Myrtle Beach

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You'll be given this information with the available room rates after you select a hotel and specify dates. Many hotels have cancellation penalties associated with their best rates. Most offer "Book Now and Pay Later" options that are less restrictive, but slightly more expensive.